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Assay Detail

CHEMBL5104491

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against chloroquine resistant Plasmodium falciparum Dd2 incubated for 48 hrs by SYBR green I fluorescence based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

An insight into the recent development of the clinical candidates for the treatment of malaria and their target proteins.
Madhav H, Hoda N.
Eur J Med Chem (2021) 210 : 112955 -112955
PubMed 33131885 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.37 8.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5177723 1 8.77
CHEMBL5192558 1 7.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5177723 IC50 = 1.7 nM 8.77
CHEMBL5192558 IC50 = 11.1 nM 7.96