Assay Detail
Binding
CHEMBL5104700
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of FGFR2 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of Cysteine-targeting Covalent Protein Kinase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.89 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3701238 | FUTIBATINIB | 4.0 | 1 | 8.89 |
| CHEMBL3939295 | H3B-6527 | 1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3701238 | FUTIBATINIB | IC50 | = | 1.3 | nM | 8.89 |
| CHEMBL3939295 | H3B-6527 | IC50 | < | 1.2 | nM | - |