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Assay Detail

CHEMBL5105475

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human K562 cells assessed as cell viability by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type K562
Confidence 1 — Organism
Curated By Autocuration

Target

K562 (CHEMBL385)
Type CELL-LINE
Organism Homo sapiens

Publication

Indoloquinolines as scaffolds for the design of potent G-quadruplex ligands.
Mendes E, Bahls B, Aljnadi IM, Paulo A.
Bioorg Med Chem Lett (2022) 72 : 128862 -128862
PubMed 35716866 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.58 5.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL219728 1 5.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL219728 IC50 = 2600.0 nM 5.58