Assay Detail
Binding
CHEMBL5106512
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human SSAO
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Combining monoamine oxidase B and semicarbazide-sensitive amine oxidase enzyme inhibition to address inflammatory disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 7.83 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5198317 | — | — | 1 | 8.40 |
| CHEMBL5204901 | — | — | 1 | 8.30 |
| CHEMBL5201033 | — | — | 1 | 8.22 |
| CHEMBL489079 | MOFEGILINE | 2.0 | 1 | 8.00 |
| CHEMBL5186190 | — | — | 1 | 7.96 |
| CHEMBL5197971 | — | — | 1 | 7.92 |
| CHEMBL5194056 | — | — | 1 | 7.72 |
| CHEMBL5196906 | — | — | 1 | 7.72 |
| CHEMBL5186898 | — | — | 1 | 7.50 |
| CHEMBL5199917 | — | — | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5198317 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL5204901 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL5201033 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL489079 | MOFEGILINE | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL5186190 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL5197971 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL5194056 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL5196906 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL5186898 | — | IC50 | = | 32.0 | nM | 7.50 |
| CHEMBL5199917 | — | IC50 | = | 288.0 | nM | 6.54 |