Assay Detail
Binding
CHEMBL5107040
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Plasmodium falciparum CDPK1 measured after 2 hrs by luciferin based luminescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Calcium-dependent protein kinase 1 (CHEMBL1908387) ↗| Type | SINGLE PROTEIN |
| Organism | Plasmodium falciparum |
Publication
Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial <i>Pf</i>GSK3/<i>Pf</i>PK6 with Activity against Blood Stage Parasites In Vitro.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.68 | 8.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1213510 | PURFALCAMINE | — | 1 | 8.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1213510 | PURFALCAMINE | IC50 | = | 2.1 | nM | 8.68 |