Assay Detail
Functional
CHEMBL5108629
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Cytotoxicity against human MCF7 cells assessed as cell growth inhibition
10
Total Activities
10
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Natural products from mangrove sediments-derived microbes: Structural diversity, bioactivities, biosynthesis, and total synthesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.72 | 6.72 |
| GI50 | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5177929 | — | — | 1 | 6.72 |
| CHEMBL3740584 | — | — | 1 | 6.72 |
| CHEMBL4441305 | — | — | 1 | 6.72 |
| CHEMBL3740707 | — | — | 1 | 6.72 |
| CHEMBL3086649 | — | — | 1 | 6.72 |
| CHEMBL3741748 | — | — | 1 | 6.72 |
| CHEMBL3086650 | — | — | 1 | 6.72 |
| CHEMBL5180764 | — | — | 1 | - |
| CHEMBL467698 | — | — | 1 | - |
| CHEMBL478807 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5177929 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL3740584 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL4441305 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL3740707 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL3086649 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL3741748 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL3086650 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL5180764 | — | IC50 | = | 7.5 | ug.mL-1 | - |
| CHEMBL467698 | — | GI50 | = | 0.11 | ug.mL-1 | - |
| CHEMBL478807 | — | GI50 | = | 0.11 | ug.mL-1 | - |