Assay Detail
Toxicity
CHEMBL5108729
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Cytotoxicity against human platelets assessed as cell growth inhibition incubated for 24 hrs
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Cell Type | Platelet |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Trends in targeting Bcl-2 anti-apoptotic proteins for cancer treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.05 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3342332 | A-1155463 | — | 1 | 8.15 |
| CHEMBL4777606 | — | — | 1 | 5.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3342332 | A-1155463 | IC50 | = | 7.1 | nM | 8.15 |
| CHEMBL4777606 | — | IC50 | = | 1136.0 | nM | 5.95 |