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Assay Detail

CHEMBL5109380

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Functional
Antiproliferative activity against human Malme-3M cells after 72 hrs by CellTiter-Glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Malme-3M
Confidence 1 — Organism
Curated By Autocuration

Target

Malme-3M (CHEMBL614021)
Type CELL-LINE
Organism Homo sapiens

Publication

Identification and structural analysis of a selective tropomyosin receptor kinase C (TRKC) inhibitor.
Wang Z, Ren J, Jia K, Zhao Y, Liang L, Cheng Z, Huang F, Zhao X, Cheng J, Song S, Sheng T, Wan W, Shu Q, Wu D, Zhang J, Lu T, Chen Y, Ran T, Lu S.
Eur J Med Chem (2022) 241 : 114601 -114601
PubMed 35872544 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.32 6.32

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5198364 1 6.32

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5198364 IC50 = 479.2 nM 6.32