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Assay Detail

CHEMBL5110675

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

An overview on Estrogen receptors signaling and its ligands in breast cancer.
Khan MZI, Uzair M, Nazli A, Chen JZ.
Eur J Med Chem (2022) 241 : 114658 -114658
PubMed 35964426 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.54 9.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1358 FULVESTRANT 4.0 1 9.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1358 FULVESTRANT IC50 = 0.29 nM 9.54