Assay Detail
Binding
CHEMBL5112296
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-prazosin from human adrenergic alpha1A receptor expressed in human HEK293 cells
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a Potent and Highly Selective Dipeptidyl Peptidase IV and Carbonic Anhydrase Inhibitor as "Antidiabesity" Agents Based on Repurposing and Morphing of WB-4101.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| Ki | 1 | 6.61 | 6.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5177166 | — | — | 1 | 6.61 |
| CHEMBL5198237 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5177166 | — | Ki | = | 245.47 | nM | 6.61 |
| CHEMBL5198237 | — | Activity | - | — | - |