Assay Detail
Functional
CHEMBL5113664
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Cytotoxicity against human Panel NCI-60 (60 carcinoma cell lines) cells assessed as cell growth inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Panel NCI-60 (60 carcinoma cell lines) |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Paradigm shift of "classical" HDAC inhibitors to "hybrid" HDAC inhibitors in therapeutic interventions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.66 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL487253 | BENDAMUSTINE | 4.0 | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL487253 | BENDAMUSTINE | IC50 | = | 2200.0 | nM | 5.66 |