Assay Detail
Functional
CHEMBL5113740
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Antifungal activity against Candida albicans assessed as fungal growth inhibition
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Candida albicans |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Tryptophan derived natural marine alkaloids and synthetic derivatives as promising antimicrobial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 5.17 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5209103 | — | — | 1 | 6.30 |
| CHEMBL5169653 | — | — | 1 | 5.55 |
| CHEMBL5170346 | — | — | 1 | 5.50 |
| CHEMBL5184372 | — | — | 1 | 5.32 |
| CHEMBL302637 | NORTOPSENTIN A | — | 1 | 5.17 |
| CHEMBL292801 | NORTOPSENTIN B | — | 1 | 5.17 |
| CHEMBL63208 | NORTOPSENTIN C | — | 1 | 5.17 |
| CHEMBL5208629 | — | — | 1 | 5.10 |
| CHEMBL5192861 | — | — | 1 | 4.85 |
| CHEMBL5186502 | — | — | 1 | 4.84 |
| CHEMBL5179552 | — | — | 1 | 4.70 |
| CHEMBL5177565 | — | — | 1 | 4.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5209103 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL5169653 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL5170346 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL5184372 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL302637 | NORTOPSENTIN A | IC50 | = | 6800.0 | nM | 5.17 |
| CHEMBL292801 | NORTOPSENTIN B | IC50 | = | 6800.0 | nM | 5.17 |
| CHEMBL63208 | NORTOPSENTIN C | IC50 | = | 6800.0 | nM | 5.17 |
| CHEMBL5208629 | — | IC50 | = | 7900.0 | nM | 5.10 |
| CHEMBL5192861 | — | IC50 | = | 14200.0 | nM | 4.85 |
| CHEMBL5186502 | — | IC50 | = | 14500.0 | nM | 4.84 |
| CHEMBL5179552 | — | IC50 | = | 19900.0 | nM | 4.70 |
| CHEMBL5177565 | — | IC50 | = | 45700.0 | nM | 4.34 |