Assay Detail
Functional
CHEMBL5113742
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Antifungal activity against Trichophyton mentagrophytes assessed as fungal growth inhibition
7
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Trichophyton mentagrophytes |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Trichophyton mentagrophytes (CHEMBL613162) ↗| Type | ORGANISM |
| Organism | Trichophyton mentagrophytes |
Publication
Tryptophan derived natural marine alkaloids and synthetic derivatives as promising antimicrobial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.67 | 6.30 |
| MIC | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5209103 | — | — | 1 | 6.30 |
| CHEMBL5184085 | — | — | 1 | 4.38 |
| CHEMBL5174827 | — | — | 1 | 4.37 |
| CHEMBL5177565 | — | — | 1 | 4.34 |
| CHEMBL5197169 | — | — | 1 | 4.32 |
| CHEMBL5170346 | — | — | 1 | 4.29 |
| CHEMBL5208629 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5209103 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL5184085 | — | IC50 | = | 42100.0 | nM | 4.38 |
| CHEMBL5174827 | — | IC50 | = | 42600.0 | nM | 4.37 |
| CHEMBL5177565 | — | IC50 | = | 45700.0 | nM | 4.34 |
| CHEMBL5197169 | — | IC50 | = | 48300.0 | nM | 4.32 |
| CHEMBL5170346 | — | IC50 | = | 51100.0 | nM | 4.29 |
| CHEMBL5208629 | — | MIC | = | 31500.0 | nM | - |