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Assay Detail

CHEMBL5113745

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Functional
Antibacterial activity against Micrococcus luteus assessed as bacterial growth inhibition
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Micrococcus luteus
Confidence 1 — Organism
Curated By Autocuration

Target

Micrococcus luteus (CHEMBL614421)
Type ORGANISM
Organism Micrococcus luteus

Publication

Tryptophan derived natural marine alkaloids and synthetic derivatives as promising antimicrobial agents.
Almeida MC, Resende DISP, da Costa PM, Pinto MMM, Sousa E.
Eur J Med Chem (2021) 209 : 112945 -112945
PubMed 33153766 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.09 5.38
MIC 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5209103 1 5.38
CHEMBL5194166 1 5.23
CHEMBL5195415 1 4.65
CHEMBL2229117 FUMIQUINAZOLINE F 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5209103 IC50 = 4200.0 nM 5.38
CHEMBL5194166 IC50 = 5900.0 nM 5.23
CHEMBL5195415 IC50 = 22600.0 nM 4.65
CHEMBL2229117 FUMIQUINAZOLINE F MIC = 276200.0 nM -