Assay Detail
Functional
CHEMBL5113746
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Antifungal activity against Aspergillus niger assessed as fungal growth inhibition
7
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Aspergillus niger |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Tryptophan derived natural marine alkaloids and synthetic derivatives as promising antimicrobial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.59 | 4.89 |
| MIC | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5170346 | — | — | 1 | 4.89 |
| CHEMBL5184085 | — | — | 1 | 4.68 |
| CHEMBL5174827 | — | — | 1 | 4.67 |
| CHEMBL5177565 | — | — | 1 | 4.64 |
| CHEMBL5182264 | — | — | 1 | 4.07 |
| CHEMBL5194055 | — | — | 1 | - |
| CHEMBL5176080 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5170346 | — | IC50 | = | 12800.0 | nM | 4.89 |
| CHEMBL5184085 | — | IC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL5174827 | — | IC50 | = | 21300.0 | nM | 4.67 |
| CHEMBL5177565 | — | IC50 | = | 22800.0 | nM | 4.64 |
| CHEMBL5182264 | — | IC50 | = | 85200.0 | nM | 4.07 |
| CHEMBL5194055 | — | MIC | = | 27500.0 | nM | - |
| CHEMBL5176080 | — | MIC | = | 26800.0 | nM | - |