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Assay Detail

CHEMBL5113778

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Binding
Displacement of [3H]SCH-23390 from porcine striatum dopamine D1 receptor incubated for 30 mins by radioligand competition binding assay based scintillation counter analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Sus scrofa
Tissue Striatum
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

D(1A) dopamine receptor (CHEMBL5067)
Type SINGLE PROTEIN
Organism Sus scrofa

Publication

Research progress in biological activities of isochroman derivatives.
Zhao Z, Kang K, Yue J, Ji X, Qiao H, Fan P, Zheng X.
Eur J Med Chem (2021) 210 : 113073 -113073
PubMed 33310287 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.41 8.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL291143 1 8.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL291143 Ki = 3.9 nM 8.41