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Assay Detail

CHEMBL5113911

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human Bcl-xL/Bak (unkown origin) incubated for 1 hr by fluorescence polarization assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Bcl-xL/BAK (CHEMBL3137283)
Type PROTEIN-PROTEIN INTERACTION
Organism Homo sapiens

Publication

Development of Mcl-1 inhibitors for cancer therapy.
Negi A, Murphy PV.
Eur J Med Chem (2021) 210 : 113038 -113038
PubMed 33333396 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.16 6.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5193670 1 6.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5193670 Ki = 700.0 nM 6.16