Assay Detail
Functional
CHEMBL5113918
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Antimalarial activity against Plasmodium falciparum K1 by 96-well microtitre plate method based scintillation counting analysis
4
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial application of quinones: A recent update.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.49 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5201440 | — | — | 2 | 6.85 |
| CHEMBL514883 | KNIPHOLONE | — | 1 | 5.97 |
| CHEMBL5181878 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5201440 | — | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL5201440 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL514883 | KNIPHOLONE | IC50 | = | 1060.0 | nM | 5.97 |
| CHEMBL5181878 | — | IC50 | = | 0.751 | ug.mL-1 | - |