Assay Detail

CHEMBL5113919

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antimalarial activity against Plasmodium falciparum NF54 by 96-well microtitre plate method based scintillation counting analysis

ChEMBL ↗

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Target

Plasmodium falciparum (CHEMBL364) ↗

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Primary target Plasmodium falciparum

CHEMBL364

Anchored from Assay target.

Protein identity Plasmodium falciparum

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Plasmodium falciparum
Confidence	1 — Organism
Curated By	Autocuration

Target

Plasmodium falciparum (CHEMBL364) ↗

Type	ORGANISM
Organism	Plasmodium falciparum

Publication

Antimalarial application of quinones: A recent update.

Patel OPS, Beteck RM, Legoabe LJ.
Eur J Med Chem (2021) 210 : 113084 -113084
PubMed 33333397 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.77	5.77

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL514883	KNIPHOLONE	—	1	5.77

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL514883	KNIPHOLONE	IC50	=	1700.0	nM	5.77