Assay Detail
Functional
CHEMBL5113925
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Antimalarial activity against Plasmodium falciparum W2 incubated for 24 hrs
7
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial application of quinones: A recent update.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.79 | 5.64 |
| IC100 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL219541 | — | — | 2 | 5.64 |
| CHEMBL4448405 | — | — | 1 | 4.80 |
| CHEMBL441441 | ALPHA-LAPACHONE | — | 1 | 4.80 |
| CHEMBL5191996 | — | — | 1 | 4.71 |
| CHEMBL15192 | LAPACHONE | 2.0 | 1 | 4.69 |
| CHEMBL15193 | LAPACHOL | — | 1 | 4.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL219541 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL4448405 | — | IC50 | = | 15800.0 | nM | 4.80 |
| CHEMBL441441 | ALPHA-LAPACHONE | IC50 | = | 15800.0 | nM | 4.80 |
| CHEMBL5191996 | — | IC50 | = | 19500.0 | nM | 4.71 |
| CHEMBL15192 | LAPACHONE | IC50 | = | 20500.0 | nM | 4.69 |
| CHEMBL15193 | LAPACHOL | IC50 | = | 80000.0 | nM | 4.10 |
| CHEMBL219541 | — | IC100 | = | 4.7 | uM | - |