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Assay Detail

CHEMBL5113940

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiplasmodial activity against Chloroquine resistant Plasmodium falciparum FcB1 incubated for 48 hrs by SYBR green I based fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Antimalarial application of quinones: A recent update.
Patel OPS, Beteck RM, Legoabe LJ.
Eur J Med Chem (2021) 210 : 113084 -113084
PubMed 33333397 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.17 6.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3398293 1 6.24
CHEMBL3398294 1 6.20
CHEMBL3398292 1 6.07

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3398293 IC50 = 580.0 nM 6.24
CHEMBL3398294 IC50 = 630.0 nM 6.20
CHEMBL3398292 IC50 = 845.0 nM 6.07