Assay Detail
Functional
CHEMBL5113966
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Antimalarial activity against drug resistant Plasmodium falciparum K1
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial application of quinones: A recent update.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 8.42 | 8.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4439519 | — | — | 1 | 8.62 |
| CHEMBL361497 | ARTESUNATE | 4.0 | 1 | 8.62 |
| CHEMBL4465998 | — | — | 1 | 8.60 |
| CHEMBL4592955 | — | — | 1 | 8.49 |
| CHEMBL4442146 | — | — | 1 | 8.19 |
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4439519 | — | IC50 | = | 2.4 | nM | 8.62 |
| CHEMBL361497 | ARTESUNATE | IC50 | = | 2.4 | nM | 8.62 |
| CHEMBL4465998 | — | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL4592955 | — | IC50 | = | 3.2 | nM | 8.49 |
| CHEMBL4442146 | — | IC50 | = | 6.5 | nM | 8.19 |
| CHEMBL76 | CHLOROQUINE | IC50 | = | 10.0 | nM | 8.00 |