Assay Detail
Binding
CHEMBL5114010
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of telomerase derived from human A2780 cell extract by TRAP assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Role of basic aminoalkyl chains in the lead optimization of Indoloquinoline alkaloids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.07 | 5.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5182039 | — | — | 1 | 5.20 |
| CHEMBL5171815 | — | — | 1 | 4.93 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5182039 | — | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL5171815 | — | IC50 | = | 11800.0 | nM | 4.93 |