Assay Detail
Functional
CHEMBL5114019
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Cytotoxicity against human SK-OV-3 cells assessed as cell growth inhibition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-OV-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Role of basic aminoalkyl chains in the lead optimization of Indoloquinoline alkaloids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.69 | 5.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL292124 | — | — | 1 | 5.20 |
| CHEMBL224248 | QUINDOLINE | — | 1 | 4.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL292124 | — | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL224248 | QUINDOLINE | IC50 | = | 66000.0 | nM | 4.18 |