Assay Detail
Functional
CHEMBL5114054
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Antileishmanial activity against Leishmania donovani amastigotes assessed as parasite growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania donovani |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Role of basic aminoalkyl chains in the lead optimization of Indoloquinoline alkaloids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.56 | 5.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2322213 | — | — | 1 | 5.01 |
| CHEMBL2322509 | — | — | 1 | 4.58 |
| CHEMBL2322216 | — | — | 1 | 4.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2322213 | — | IC50 | = | 9700.0 | nM | 5.01 |
| CHEMBL2322509 | — | IC50 | = | 26000.0 | nM | 4.58 |
| CHEMBL2322216 | — | IC50 | = | 79000.0 | nM | 4.10 |