Assay Detail
Binding
CHEMBL5114188
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Displacement of [3H]AMPA from NMDA receptor (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.43 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL343863 | — | — | 1 | 5.80 |
| CHEMBL413125 | — | — | 1 | 5.70 |
| CHEMBL290555 | — | — | 1 | 5.34 |
| CHEMBL290738 | — | — | 1 | 5.34 |
| CHEMBL356281 | — | — | 1 | 4.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL343863 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL413125 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL290555 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL290738 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL356281 | — | IC50 | = | 11300.0 | nM | 4.95 |