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Assay Detail

CHEMBL5114191

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]NMDA from NMDA receptor (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Glutamate [NMDA] receptor (CHEMBL2094124)
Type PROTEIN COMPLEX GROUP
Organism Homo sapiens

Publication

Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.
Jiang X, Wu K, Bai R, Zhang P, Zhang Y.
Eur J Med Chem (2022) 229 : 114085 -114085
PubMed 34998058 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.76 7.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL450325 1 7.05
CHEMBL61720 1 6.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL450325 IC50 = 90.0 nM 7.05
CHEMBL61720 IC50 = 350.0 nM 6.46