Assay Detail
Functional
CHEMBL5114328
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Inhibition of antigen-induced release of histamine (AIR) from rat peritoneal mast cells (RMC)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | Mast cell |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.31 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5201899 | — | — | 1 | 7.00 |
| CHEMBL121101 | — | — | 1 | 6.40 |
| CHEMBL74 | CROMOLYN SODIUM | 4.0 | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5201899 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL121101 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL74 | CROMOLYN SODIUM | IC50 | = | 3000.0 | nM | 5.52 |