Assay Detail
Functional
CHEMBL5114337
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Vasorelaxant activity in dog coronary arteries
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Canis lupus familiaris |
| Tissue | Coronary artery |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.37 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92216 | — | — | 1 | 6.52 |
| CHEMBL91789 | — | — | 1 | 5.77 |
| CHEMBL312971 | — | — | 1 | 4.96 |
| CHEMBL93452 | — | — | 1 | 4.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92216 | — | EC50 | = | 300.0 | nM | 6.52 |
| CHEMBL91789 | — | EC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL312971 | — | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL93452 | — | EC50 | = | 59000.0 | nM | 4.23 |