Assay Detail
Binding
CHEMBL5114339
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Inhibition of cGMP-dependent 3',5'-cyclic phosphodiesterase (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.25 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL91789 | — | — | 1 | 6.40 |
| CHEMBL92216 | — | — | 1 | 5.16 |
| CHEMBL93452 | — | — | 1 | 4.85 |
| CHEMBL312971 | — | — | 1 | 4.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL91789 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL92216 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL93452 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL312971 | — | IC50 | = | 27000.0 | nM | 4.57 |