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Assay Detail

CHEMBL5114527

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human camptothecin-resistant K5 cells assessed as cell growth inhibition measured after 4 days by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type K5
Confidence 1 — Organism
Curated By Autocuration

Target

K5 (CHEMBL2366152)
Type CELL-LINE
Organism Homo sapiens

Publication

Topoisomerase I inhibitors: Challenges, progress and the road ahead.
Talukdar A, Kundu B, Sarkar D, Goon S, Mondal MA.
Eur J Med Chem (2022) 236 : 114304 -114304
PubMed 35413618 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.97 4.97

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5194864 1 4.97

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5194864 IC50 = 10800.0 nM 4.97