Assay Detail
Binding
CHEMBL5117467
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of beta-lactamase SHV-12 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacteria |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Triazole-substituted phenylboronic acids as tunable lead inhibitors of KPC-2 antibiotic resistance.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.13 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL257468 | — | — | 1 | 7.40 |
| CHEMBL3586556 | — | — | 1 | 6.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL257468 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL3586556 | — | IC50 | = | 140.0 | nM | 6.85 |