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Assay Detail

CHEMBL5117867

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Vesicular stomatitis virus assessed as viral growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Vesicular stomatitis virus
Confidence 1 — Organism
Curated By Autocuration

Target

Vesicular stomatitis virus (CHEMBL613739)
Type ORGANISM
Organism Vesicular stomatitis virus

Publication

Synthesis and biological evaluation of novel pentanediamide derivatives as S-adenosyl-l-homocysteine hydrolase inhibitors.
Lv YB, Chen C, Yu QM, Lyu L, Peng YF, Tan XD.
Bioorg Med Chem Lett (2022) 72 : 128880 -128880
PubMed 35809817 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 4.41 4.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5200876 1 4.41
CHEMBL5202341 1 -
CHEMBL5182992 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5200876 EC50 = 38910.0 nM 4.41
CHEMBL5202341 EC50 > 100000.0 nM -
CHEMBL5182992 EC50 > 100000.0 nM -