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Assay Detail

CHEMBL5117868

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Respiratory syncytial virus assessed as viral growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Respiratory syncytial virus
Confidence 1 — Organism
Curated By Autocuration

Target

Respiratory syncytial virus (CHEMBL612679)
Type ORGANISM
Organism Respiratory syncytial virus

Publication

Synthesis and biological evaluation of novel pentanediamide derivatives as S-adenosyl-l-homocysteine hydrolase inhibitors.
Lv YB, Chen C, Yu QM, Lyu L, Peng YF, Tan XD.
Bioorg Med Chem Lett (2022) 72 : 128880 -128880
PubMed 35809817 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 4.30 4.56

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5202341 1 4.56
CHEMBL5200876 1 4.04
CHEMBL5182992 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5202341 EC50 = 27400.0 nM 4.56
CHEMBL5200876 EC50 = 91080.0 nM 4.04
CHEMBL5182992 EC50 > 100000.0 nM -