Assay Detail
Toxicity
CHEMBL5118418
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Cytotoxicity against human L02 cells measured after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Cell Type | L02 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New brefeldin A-cinnamic acid ester derivatives as potential antitumor agents: Design, synthesis and biological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.28 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL19980 | BREFELDIN A | — | 1 | 7.00 |
| CHEMBL5189836 | — | — | 1 | 5.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL19980 | BREFELDIN A | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5189836 | — | IC50 | = | 2810.0 | nM | 5.55 |