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Assay Detail

CHEMBL5121304

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Binding
Inhibition of xanthine oxidase (unknown origin) at 10 uM using xanthine as substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Xanthine dehydrogenase/oxidase (CHEMBL1929)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Isolation and biological activity of azocine and azocane alkaloids.
Lee S, Sperry J.
Bioorg Med Chem (2022) 54 : 116560 -116560
PubMed 34923389 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.21 6.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1467 ALLOPURINOL 4.0 1 6.22
CHEMBL285671 APPARICINE 1 6.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1467 ALLOPURINOL IC50 = 600.0 nM 6.22
CHEMBL285671 APPARICINE IC50 = 650.0 nM 6.19