Assay Detail
Functional
CHEMBL5121371
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Antimalarial activity against Plasmodium falciparum 3D7
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structural modification aimed for improving solubility of lead compounds in early phase drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.30 | 7.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2030016 | — | — | 1 | 7.51 |
| CHEMBL4459053 | — | — | 1 | 7.48 |
| CHEMBL2030298 | — | — | 1 | 7.27 |
| CHEMBL2030038 | — | — | 1 | 6.93 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2030016 | — | IC50 | = | 31.0 | nM | 7.51 |
| CHEMBL4459053 | — | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL2030298 | — | IC50 | = | 54.0 | nM | 7.27 |
| CHEMBL2030038 | — | IC50 | = | 117.0 | nM | 6.93 |