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Assay Detail

CHEMBL5121744

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Functional
Antiproliferative activity against human ovarian cancer cells after 72 hrs by CellTiter 96 AQueous One Solution Cell Proliferation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Ovarian cancer cell line
Confidence 1 — Organism
Curated By Autocuration

Target

Ovarian cancer cell line (CHEMBL613895)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of Anticancer Agents of Diverse Natural Origin.
Aldrich LN, Burdette JE, Carcache de Blanco E, Coss CC, Eustaquio AS, Fuchs JR, Kinghorn AD, MacFarlane A, Mize BK, Oberlies NH, Orjala J, Pearce CJ, Phelps MA, Rakotondraibe LH, Ren Y, Soejarto DD, Stockwell BR, Yalowich JC, Zhang X.
J Nat Prod (2022) 85 : 702 -719
PubMed 35213158 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.36 7.36

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL449686 STREBLOSIDE 1 7.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL449686 STREBLOSIDE IC50 = 44.0 nM 7.36