Assay Detail
Binding
CHEMBL5121892
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Inhibition of G6PD (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Boosting the Discovery of Small Molecule Inhibitors of Glucose-6-Phosphate Dehydrogenase for the Treatment of Cancer, Infectious Diseases, and Inflammation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.56 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2057293 | — | — | 1 | 6.00 |
| CHEMBL2057300 | — | — | 1 | 5.92 |
| CHEMBL2057640 | — | — | 1 | 5.92 |
| CHEMBL272195 | EPIANDROSTERONE | — | 1 | 5.03 |
| CHEMBL90593 | PRASTERONE | 4.0 | 1 | 4.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2057293 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL2057300 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL2057640 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL272195 | EPIANDROSTERONE | IC50 | = | 9400.0 | nM | 5.03 |
| CHEMBL90593 | PRASTERONE | IC50 | = | 11300.0 | nM | 4.95 |