Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5121898

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against Chloroquine-resistant Plasmodium falciparum Dd2 incubated for 48 hrs followed by [3H]-hypoxanthine addition measured after 24 hrs by microdilution method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Boosting the Discovery of Small Molecule Inhibitors of Glucose-6-Phosphate Dehydrogenase for the Treatment of Cancer, Infectious Diseases, and Inflammation.
Koperniku A, Garcia AA, Mochly-Rosen D.
J Med Chem (2022) 65 : 4403 -4423
PubMed 35239352 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.43 5.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2170943 1 5.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2170943 IC50 = 3700.0 nM 5.43