Assay Detail
Binding
CHEMBL5121900
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Binding affinity to Plasmodium falciparum GluPho
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Boosting the Discovery of Small Molecule Inhibitors of Glucose-6-Phosphate Dehydrogenase for the Treatment of Cancer, Infectious Diseases, and Inflammation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 4.41 | 4.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5190364 | — | — | 1 | 4.64 |
| CHEMBL5202473 | — | — | 1 | 4.49 |
| CHEMBL4161382 | — | — | 1 | 4.46 |
| CHEMBL4172694 | — | — | 1 | 4.37 |
| CHEMBL4162165 | — | — | 1 | 4.34 |
| CHEMBL4169301 | — | — | 1 | 4.16 |
| CHEMBL4159624 | — | — | 1 | - |
| CHEMBL4167547 | — | — | 1 | - |
| CHEMBL4172838 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5190364 | — | Ki | = | 22800.0 | nM | 4.64 |
| CHEMBL5202473 | — | Ki | = | 32400.0 | nM | 4.49 |
| CHEMBL4161382 | — | Ki | = | 34400.0 | nM | 4.46 |
| CHEMBL4172694 | — | Ki | = | 42900.0 | nM | 4.37 |
| CHEMBL4162165 | — | Ki | = | 45600.0 | nM | 4.34 |
| CHEMBL4169301 | — | Ki | = | 68800.0 | nM | 4.16 |
| CHEMBL4159624 | — | Ki | = | 259000.0 | nM | - |
| CHEMBL4167547 | — | Ki | = | 289000.0 | nM | - |
| CHEMBL4172838 | — | Ki | > | 76100.0 | nM | - |