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Assay Detail

CHEMBL5121902

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Plasmodium falciparum GluPho
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Plasmodium falciparum
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Boosting the Discovery of Small Molecule Inhibitors of Glucose-6-Phosphate Dehydrogenase for the Treatment of Cancer, Infectious Diseases, and Inflammation.
Koperniku A, Garcia AA, Mochly-Rosen D.
J Med Chem (2022) 65 : 4403 -4423
PubMed 35239352 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.25 6.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4165870 1 6.72
CHEMBL5207151 1 5.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4165870 IC50 = 190.0 nM 6.72
CHEMBL5207151 IC50 = 1700.0 nM 5.77