Assay Detail

CHEMBL5121919

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Functional

Antiproliferative activity against human SK-OV-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay

ChEMBL ↗

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Target

SK-OV-3 (CHEMBL614925) ↗

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SK-OV-3 (CHEMBL614925) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target SK-OV-3

CHEMBL614925

Anchored from Assay target.

Protein identity SK-OV-3

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	SK-OV-3
Confidence	1 — Organism
Curated By	Autocuration

Target

SK-OV-3 (CHEMBL614925) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Incorporating Selenium into Heterocycles and Natural Products─From Chemical Properties to Pharmacological Activities.

Hou W, Xu H.
J Med Chem (2022) 65 : 4436 -4456
PubMed 35244394 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.29	4.29

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL271227	ABIRATERONE ACETATE	4.0	1	4.29

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL271227	ABIRATERONE ACETATE	IC50	=	51510.0	nM	4.29