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Assay Detail

CHEMBL5124407

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against SARS-CoV-2 by cell based assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Severe acute respiratory syndrome coronavirus 2
Confidence 1 — Organism
Curated By Autocuration

Target

SARS-CoV-2 (CHEMBL4303835)
Type ORGANISM
Organism Severe acute respiratory syndrome coronavirus 2

Publication

Peptidomimetics: An Overview of Recent Medicinal Chemistry Efforts toward the Discovery of Novel Small Molecule Inhibitors.
Li Petri G, Di Martino S, De Rosa M.
J Med Chem (2022) 65 : 7438 -7475
PubMed 35604326 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 11 6.92 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5194912 1 7.00
CHEMBL5178275 1 7.00
CHEMBL5174145 1 6.96
CHEMBL5175540 1 6.72
CHEMBL5195656 1 -
CHEMBL5190394 1 -
CHEMBL5172701 1 -
CHEMBL5188945 1 -
CHEMBL5184284 1 -
CHEMBL5173283 1 -
CHEMBL2315036 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5194912 EC50 = 100.0 nM 7.00
CHEMBL5178275 EC50 = 100.0 nM 7.00
CHEMBL5174145 EC50 = 110.0 nM 6.96
CHEMBL5175540 EC50 = 190.0 nM 6.72
CHEMBL5195656 EC50 - -
CHEMBL5190394 EC50 - -
CHEMBL5172701 EC50 - -
CHEMBL5188945 EC50 - -
CHEMBL5184284 EC50 - -
CHEMBL5173283 EC50 - -
CHEMBL2315036 EC50 - -