Assay Detail
Binding
CHEMBL5124446
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to beta-catenin/E-cadherin (unknown origin) assessed as inhibition constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Catenin beta-1/Cadherin-1 (CHEMBL4888449) ↗| Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
Publication
Peptidomimetics: An Overview of Recent Medicinal Chemistry Efforts toward the Discovery of Novel Small Molecule Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.70 | 4.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5189409 | — | — | 1 | 4.89 |
| CHEMBL4451478 | — | — | 1 | 4.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5189409 | — | Ki | = | 13000.0 | nM | 4.89 |
| CHEMBL4451478 | — | Ki | = | 32000.0 | nM | 4.50 |