Assay Detail
Binding
CHEMBL5124524
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to His-tagged human STAT1 (132 to 713 residues) expressed in Escherichia coli Rosette (DE3) assessed as dissociation constant using SD-45-FL as substrate measured after 1 hr by Fluorescence Polarization assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Signal transducer and activator of transcription 1-alpha/beta (CHEMBL6101) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Selectivity through Targeted Protein Degradation (TPD).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4452527 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4452527 | — | Kd | = | 1000.0 | nM | 6.00 |