Assay Detail
Binding
CHEMBL5125659
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to PPARdelta (unknown origin) by TR-FRET based LanthaScreen competitive binding assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor delta (CHEMBL3979) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Design, Synthesis, and Biological Activity of l-1'-Homologated Adenosine Derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.99 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38943 | GW501516 | 2.0 | 1 | 7.10 |
| CHEMBL5208616 | — | — | 1 | 6.00 |
| CHEMBL5208465 | — | — | 1 | 5.47 |
| CHEMBL4758410 | — | — | 1 | 5.37 |
| CHEMBL21241 | GW7647 | — | 1 | - |
| CHEMBL434063 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38943 | GW501516 | Ki | = | 80.0 | nM | 7.10 |
| CHEMBL5208616 | — | Ki | = | 1000.0 | nM | 6.00 |
| CHEMBL5208465 | — | Ki | = | 3400.0 | nM | 5.47 |
| CHEMBL4758410 | — | Ki | = | 4300.0 | nM | 5.37 |
| CHEMBL21241 | GW7647 | Ki | - | — | - | |
| CHEMBL434063 | — | Ki | - | — | - |