Assay Detail
Binding
CHEMBL5125668
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at PPARdelta (unknown origin) by TR-FRET assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor delta (CHEMBL3979) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Design, Synthesis, and Biological Activity of l-1'-Homologated Adenosine Derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.08 | 5.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL592652 | — | — | 1 | 5.47 |
| CHEMBL4758410 | — | — | 1 | 5.03 |
| CHEMBL5208616 | — | — | 1 | 4.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL592652 | — | EC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL4758410 | — | EC50 | = | 9300.0 | nM | 5.03 |
| CHEMBL5208616 | — | EC50 | = | 18800.0 | nM | 4.73 |