Assay Detail
Functional
CHEMBL5126307
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Induction of ROS production in human polymorphonuclear neutrophils incubated for 10 mins by DHE staining based fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Neutrophil |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cryptic Epoxytiglianes from the Kernels of the Blushwood Tree (<i>Fontainea picrosperma</i>).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.34 | 7.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5203763 | — | — | 1 | 7.78 |
| CHEMBL3989916 | TIGILANOL TIGLATE | 2.0 | 1 | 6.90 |
| CHEMBL5176212 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5203763 | — | EC50 | = | 16.7 | nM | 7.78 |
| CHEMBL3989916 | TIGILANOL TIGLATE | EC50 | = | 125.0 | nM | 6.90 |
| CHEMBL5176212 | — | EC50 | > | 3627.0 | nM | - |