Assay Detail
Functional
CHEMBL5126777
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human NCI-H460 cells assessed as cell growth inhibition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H460 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Renieramycin-type alkaloids from marine-derived organisms: Synthetic chemistry, biological activity and structural modification.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.20 | 8.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL451147 | RENIERAMYCIN M | — | 1 | 8.23 |
| CHEMBL5207300 | — | — | 1 | 8.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL451147 | RENIERAMYCIN M | IC50 | = | 5.9 | nM | 8.23 |
| CHEMBL5207300 | — | IC50 | = | 6.7 | nM | 8.17 |